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Protein Biochemistry
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GSK2606414
GSK2606414 from Cayman Chemical
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Citations:
(3)
Supplier Page
Supplier Page from
Cayman Chemical for
GSK2606414
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Description
A selective PERK inhibitor (IC50 = 0.4 nM); inhibits PERK activation in cells and the growth of a human tumor xenograft in mice
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
GSK2606414
Company
Cayman Chemical
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
17376
Format
A crystalline solid
Research Area
Cancer, Cell Signaling, Neurodegenerative Disorders, Neuroscience
Molecular Weight
451.4
Quantity
5 mg
Purity
≥98%
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway
Cancer Research Communications
August 18, 2023
Inyoung Lee, Miriam Doepner, Jillian Weissenrieder, Ariana D. Majer, Sophia Mercado, Angela Estell, Christopher A. Natale, Pamela J. Sung, J. Kevin Foskett, Martin P. Carroll,
et al.
this study include the IRE1α
inhibitor
Kira6
(
Cayman
,
19151
) and PERK
inhibitor
GSK2606414
(
Cayman
,
17376
).
GPER
antagonist G-36 (
Cayman
,
14397
) was used to block
CREB
phosphorylation.
Thapsigargin
(
Cayman
,
(2)
PERK-STING-RIPK3 pathway facilitates cognitive impairment by inducing neuronal necroptosis in sepsis-associated encephalopathy
CNS neuroscience & therapeutics
April 1, 2023
Xiaofeng G, You W, Qi J, Hongwei M, Zhongmin F, Shiquan W, Lixia D, Yuliang P, Zongping F, Xijing Z.
AAV‐hSyn (Brain VTA, Wuhan, China). In order to inject the
PERK
inhibitor
GSK2606414
(
Cayman
, Item No
17376
), we placed a cannula in the lateral ventricle (ML: +1.00 mm; AP: −0.50 mm; DV: −1.50 mm) of
mice
. The
(3)
The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPR
ER
Cell
November 27, 2019
Schinzel RT, Higuchi-Sanabria R, Shalem O, Moehle EA, Webster BM, Joe L, Bar-Ziv R, Frankino PA, Durieux J, Pender C,
et al
.
370–86–5 Gentamicin,VWR,17–5182
GlutaMAX supplement
,
Thermo Fisher
,
35050
–061
GSK2606414
,
Cayman Chemical
,
17376
Herculase II Fusion DNA Polymerase
,
Agilent
,
600677
"Hyaluronan, various sizes",
R&D Systems
,
GLR001
"Hyaluronidase,
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GSK2606414 from Cayman Chemical
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